In vivo Mr imaging at 21.1 T

In vivo magnetic resonance (Mr) imaging and spectroscopy are expanding our capability to observe and investigate many biomedical processes without invasive interventions. The unique 900-Mhz ultra-wide bore (uWB) 21.1 tesla magnet built at the Magnet lab in Tallahassee provides unprecedented opportunities to examine living systems. in this report, we present our first experiences and the results of in vivo Mr imaging at the highest field available for such studies. The ability to conduct in vivo Mr imaging experiments was achieved as a result of multiple steps taken over the past few months. This work comprised designing and fabricating coils and probes, certifying facilities for animals, and gaining institutional approval for animal research. it also included the installation of an anesthesia station and animal physiological monitoring system. The Magnet lab now has its own animal facility conveniently located in close proximity to the Mr scanners and consists of animal housing rooms and animal procedural spaces. These accomplishments afford opportunities for internal and external users to run a variety of Mr imaging experiments using the Magnet lab world-record 900 uWB magnet.